Protein-Bound Acrolein
نویسندگان
چکیده
منابع مشابه
Protein-bound acrolein: potential markers for oxidative stress.
Acrolein (CH2==CH---CHO) is known as a ubiquitous pollutant in the environment. Here we show that this notorious aldehyde is not just a pollutant, but also a lipid peroxidation product that could be ubiquitously generated in biological systems. Upon incubation with BSA, acrolein was rapidly incorporated into the protein and generated the protein-linked carbonyl derivative, a putative marker of ...
متن کاملIntense correlation between brain infarction and protein-conjugated acrolein.
BACKGROUND AND PURPOSE We recently found that increases in plasma levels of protein-conjugated acrolein and polyamine oxidases, enzymes that produce acrolein, are good markers for stroke. The aim of this study was to determine whether the level of protein-conjugated acrolein is increased and levels of spermine and spermidine, the substrates of acrolein production, are decreased at the locus of ...
متن کاملAcrolein Reference Exposure Levels
Acrolein is a powerful irritant. Due to its highly reactive nature, the effects of acrolein are generally limited to the site of contact; skin, eyes and mucous membranes. Inhalation exposure to low levels (≤ 1 ppm) causes irritation of the eyes, nose and throat. Acute exposures to levels above 1 ppm result in mucous hypersecretion and exacerbation of allergic airway response in animal models. M...
متن کاملAcrolein Reference Exposure Levels
Acrolein is a powerful irritant. Due to its highly reactive nature, the effects of acrolein are generally limited to the site of contact; skin, eyes and mucous membranes. Inhalation exposure to low levels (≤ 1 ppm) causes irritation of the eyes, nose and throat. Moderately higher exposures may result in severe lacrimation, and irritation of the mucous membranes of the respiratory tract. Death d...
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The development of atherosclerotic changes and thromboembolism are common features in homocystinurics. Hence, we postulate a positive correlation between the level of homocyst(e)ine in the blood and the occurrence of coronary artery disease. Homocysteine is found either as free homocystine, cysteine-homocysteine mixed disulfide, or protein-bound homocyst(e)ine. In nonhomocystinuric subjects, mo...
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ژورنال
عنوان ژورنال: Journal of Neurochemistry
سال: 1999
ISSN: 0022-3042
DOI: 10.1046/j.1471-4159.1999.0720751.x